Résultats des tests de spécification. Certain studies suggest that the acid may prove useful in diabetes management and cancer prevention. The measurement of the melting point allows determining the addition mode of the bromine to the double bond. Know about technical details of Cinnamaldehyde like: chemical name, chemistry structure, formulation, uses, toxicity, action, side effects and more at Pharmacompass.com. Beilstein/REAXYS Number 1905952 . In the pharmaceutical industry, it is used in the synthesis of important drugs for the treatment of coronary heart disease. risk assessment of related esters and alcohols of cinnamic acid and cinnamyl alcohol (see Table 1). [7] Another way of preparing cinnamic acid is by the Knoevenagel condensation reaction. There was a study made in 1995 that concluded the compound’s potential in cancer intervention. These esters are important components of perfumes. Cinnamic acid (C 9 H 8 O 2) is structurally similar and occurs in cinnamon, cloves, black pepper, coriander and turmeric. Cinnamic acid deriv. [4] Cinnamic acid is a precursor to the sweetener aspartame via enzyme-catalysed amination to give phenylalanine. It is used as a flavoring, in perfumes, and is a source to a large number of other natural substances. It has a role as a plant metabolite. It is created by the deamination of phenylalanine and it is then itself converted to any of the various polyphenols synthesized by plants. The lack of data on cinnamic acid makes identifying the body systems that it supports difficult. We now show that cinnamic acid induces cytostasis and a reversal of malignant properties of human tumor cells in vitro. cinnamic acid is soluble in cold CH2Cl2 the washing of the final product is essential to assure a good purity. Cinnamic acid has a honey-like odor;[2] it and its more volatile ethyl ester (ethyl cinnamate) are flavor components in the essential oil of cinnamon, in which related cinnamaldehyde is the major constituent. It can be used as apple flavor, cherry flavor, fruit flavor, and floral flavor. A major use is as a precursor to produce methyl cinnamate, ethyl cinnamate, and benzyl cinnamate for the perfume industry. Cinnamic acid is a derived compound that has been used as a flavor enhancer or as a crucial component in perfumes. [5] In 1890, Rainer Ludwig Claisen described the synthesis of ethyl cinnamate via the reaction of ethyl acetate with benzaldehyde in the presence of sodium as base. Cinnamic acid (C 9 H 8 O 2) is an organic acid isolated from cinnamon bark and generally used as a common food additive being antimicrobial against common postharvest pathogen such. Cinnamic acid uses. [5], Cinnamic acid is a central intermediate in the biosynthesis of a myriad of natural products including lignols (precursors to lignin and lignocellulose), flavonoids, isoflavonoids, coumarins, aurones, stilbenes, catechin, and phenylpropanoids. Cinnamic acid, a naturally occurring aromatic fatty acid of low toxicity, has a long history of human exposure. Its uses for medicine have only been studied recently. Substance identity Substance identity. Cinnamic acid is a white crystalline hydroxycinnamic acid, which is slightly soluble in water. It is not intended as a substitute for professional advice of any kind. Â. Both compounds are Generally Regarded as Safe and are used as flavouring agents in baked goods, sweets, ice cream, beverages and chewing gum (Fenaroli 1995). trans-Cinnamic acid. It can also be prepared by oxidation of cinnamaldehyde, condensation of benzal chloride and sodium acetate (followed by acid hydrolysis), and the Perkin reaction. Some of them may become new cosmetic ingredients in the future. Cinnamic acid is an organic compound with the formula C6H5CH=CHCOOH. It is an organic acid isolated from cinnamon bark or benzoin. Either variety is generally used for the manufacture of dyes, flavors, and certain pharmaceuticals. [10], InChI=1S/C9H8O2/c10-9(11)7-6-8-4-2-1-3-5-8/h1-7H,(H,10,11)/b7-6+, InChI=1/C9H8O2/c10-9(11)7-6-8-4-2-1-3-5-8/h1-7H,(H,10,11)/b7-6+, Except where otherwise noted, data are given for materials in their, Institute for Occupational Safety and Health, The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals, Ullmann's Encyclopedia of Industrial Chemistry, "Zur Darstellung der Zimmtsäure und ihrer Homologen", "Determination of Abraham model solute descriptors for the monomeric and dimeric forms of, https://en.wikipedia.org/w/index.php?title=Cinnamic_acid&oldid=988839041, Wikipedia articles incorporating a citation from the 1911 Encyclopaedia Britannica with Wikisource reference, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Creative Commons Attribution-ShareAlike License, This page was last edited on 15 November 2020, at 15:36. In broad strokes, cinnamic acid helps the gastrointestinal system as it — allegedly — helps balance insulin levels. Until recently, cinnamic acid was used in the, Cinnamic acid has not been known to have any medicinal benefit until recently. Cinnamic acid is an organic compound with the formula C6H5CH=CHCOOH. It is a white crystalline compound that is slightly soluble in water, and freely soluble in many organic solvents. Linear Formula C 6 H 5 CH=CHCOOH . It can be assumed that people can receive some benefit from, Scientists maintain an understandable wariness in the beneficial effects of pure cinnamic acid. It exists as both a cis and a trans isomer, although the latter is more common. Truth Publishing International, LTD. is not responsible for content written by contributing authors. Needless to say, it is possible according to the invention to use cinnamic acid or its derivatives alone or as a mixture. Cinnamic acid is an odorless white crystalline acid that has only been recently studied for its potential in cancer prevention. Its uses for medicine have only been studied recently. EC Number 205-398-1. Rosmarinic acid (RosA) ( 3 ), a secondary metabolite in rosemary and basil, is used in the traditional treatment of inflammatory disorders such as arthritis. Despite aspartame’s negative health effects on the body, cinnamic acid is in itself quite healthy. Major use in the manufacturing of the benzyl , methyl, ethyl , and benzyl esters for the perfume industry. It is used in the manufacture of methyl, ethyl, and benzyl esters for perfume industry. trans-Cinnamic acid. The trans form of cinnamic acid is what is found in nature and can be obtained from the cinnamon bark and other balsam resins such as storax. From oil of cinnamon, or from balsams such as storax acid was used in the synthesis important... 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